PKDX Research Associate, In Vivo
Company: Merck KGaA
Posted on: September 14, 2022
A career with EMD Serono is an ongoing journey of discovery: our
60,300 people are shaping how the world lives, works and plays
through next generation advancements in Healthcare, Life Science
and Electronics. For more than 350 years and across the world we
have passionately pursued our curiosity to find novel and vibrant
ways of enhancing the lives of others. EMD Serono is a business of
Merck KGaA, Darmstadt, Germany.
United As One for Patients, our purpose in Healthcare is to help
create, improve and prolong lives. We develop medicines,
intelligent devices and innovative technologies in therapeutic
areas such as Oncology, Neurology and Fertility. Our teams work
together across 6 continents with passion and relentless curiosity
in order to help patients at every stage of life. Joining our
Healthcare team is becoming part of a diverse, inclusive and
flexible working culture, presenting great opportunities for
personal development and career advancement across the globe.
This role does not offer sponsorship for work authorization.
External applicants must be eligible to work in the US.
The New Chemical Entities Drug Metabolism and Pharmacokinetics (NCE
DMPK) department at EMD Serono Research and Development Institute
in Billerica, MA is hiring a Research Associate for performing in
vivo pharmacokinetics studies in preclinical species. The NCE DMPK
department is responsible for the overall non-clinical drug
disposition contribution to small molecule projects, to fulfill
internal and regulatory requirements with emphasis on absorption,
distribution, and metabolism in order to support an integrated
evaluation of activity, toxicity and value of our compounds. The
Research Associate is a laboratory-based role within Discovery
DMPK. You will contribute to project progression by performing
pharmacokinetics studies with NCEs, primarily in rats and mice.
* Planning and setting up in-life PK studies in rodents
* Dosing and tissue sampling to support PK, PK/PD experiments with
* Providing support and/or technical assistance to research staff
with procedures including restraint, medication, dosing, specimen
collection and euthanasia of animals as needed
* Contributing to the design and implementation of in vivo
* Providing training on technical skills for junior level
associates as well as new members of the vivarium and scientific
staff, as needed
* Maintaining all associated records for studies including an
electronic lab notebook
* Maintaining relevant laboratory equipment for optimal
productivity, monitoring inventory, and purchasing supplies
Who you are:
* High School diploma or GED with 5+ years of experience in animal
handling and dosing, or a Bachelor's degree in Biology,
Pharmacology or similar Science with 2+ years of experience in
animal handling and dosing, or an associate degree in Laboratory
Animal Science/Technology or similar Science field with 3+ years of
experience in animal handling and dosing
* Proficiency in basic rodent techniques: PO, IP, SQ, IM, IV
injections; blood collection via tail and/or submandibular vein,
cardiac puncture; euthanasia, etc.
* Experience with collecting tissues from PK studies and preparing
samples for analysis
* Experience in handling cannulated animals
* Experience conducting PK, PK/PD and in vivo efficacy
* Rodent colony management experience, including an understanding
of animal health checks, record keeping, etc.
* Experience maintaining documents for compliance and good
* Ability to work independently and to interact well with
co-workers conducting in vivo experiments
What we offer: We are curious minds that come from a broad range of
backgrounds, perspectives, and life experiences.
We celebrate all dimensions of diversity. We believe that it drives
excellence, innovation, and human progress. We care about our
customers, patients, and our rich mix of people. This diversity
strengthens our ability to lead in science and technology.
We are committed to creating access and opportunities for all and
empower you to fulfil your ambitions. Our diverse businesses offer
various career moves to seek new horizons.
Join us in building a culture of inclusion and belonging that
impacts millions and empowers everyone to bring their curiosity to
Curious? Chat with one of our curious minds on our interactive
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If you would like to know more about what diversity, equity, and
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If you are a resident of NYC, Connecticut or Colorado, you are
eligible to receive additional information about the compensation
and benefits, which we will provide upon request. You may contact
855 444 5678 from 8:00am to 5:30pm ET Monday through Friday, for
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Employment Opportunity applies to all policies and programs
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made a good faith report of discrimination.
As an employee of the Company, you will be required to comply with
all of the Company's COVID-19 safety protocols and policies. The
organization has currently suspended enforcement of its COVID-19
Vaccination Policy, but that policy may be reinstated by the
Company in its discretion.
Job Requisition ID: 250147
Career Level: C - Professional (1-3 years)
Working time model: full-time
North America Disclosure
The Company is committed to accessibility in its workplaces,
including during the job application process. Applicants who may
require accommodation during the application process should speak
with our Candidate Services team at 844-655-6466
from8:00amto5:30pmET Monday through Friday.If you are a resident of
a Connecticut or Colorado, you are eligible to receive additional
information about the compensation and benefits, which we will
provide upon request. You may contact855 444 5678from 8:00am to
5:30pm ET Mondaythrough Friday, for assistance.
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Associate, Research, Healthcare
Keywords: Merck KGaA, Billerica , PKDX Research Associate, In Vivo, Other , Billerica, Massachusetts
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