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Oncology Quantitative Systems Pharmacology Modeler - Quantitative Solutions

Company: Takeda Pharmaceutical
Location: Billerica
Posted on: June 12, 2022

Job Description:

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.Job DescriptionOncology Quantitative Systems Pharmacology Modeler Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Oncology Quantitative Systems Pharmacology Modeler in our Cambridge, MA office.At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.Here, you will be a vital contributor to our inspiring, bold mission.POSITION OBJECTIVES:This role requires a mechanistic modeler working in the Quantitative Solutions group in Preclinical & Translational Sciences to support global drug development by building quantitative systems pharmacology models for oncology with an emphasis on immunologic mechanisms of action.Collaborate with clinical pharmacology, clinical research, drug discovery, drug metabolism & pharmacokinetics, and translational medicine to develop mathematical models to understand the targeted biological pathways and exposure-response/safety relationship of novel therapeutic agents.Responsible for implementing the right modeling & simulation strategy to assist with drug development, establish PK/PD relationships and create mechanistic pharmacology models to support project needs.Essential qualifications include in-depth understanding of biochemistry, hematology, immunology, numerical methods, as well as hands-on experience with modeling software, and ability to clearly present modeling and simulation findings.POSITION ACCOUNTABILITIES:This is an exciting opportunity at the interface between clinical pharmacology, clinical research, drug discovery, drug metabolism, and translational medicine to influence drug development.Work with pre-existing quantitative systems pharmacology (QSP) platforms as well as design and build fit-for-purpose multi-scale QSP models to support dose and schedule determination, study design, biomarker selection and efficacy predictions.EDUCATION, BEHAVIORAL COMPETENCIES AND SKILLS: Ph.D/Pharm.D/M.D with training in chemical or biomedical engineering, pharmaceutical sciences, mathematics, statistics, or equivalent area with at least 2 years of industry experience in mathematical modeling of biological systems. Job title is flexible based on experience.Strong competency in coding and running modeling and simulation related software such as Matlab, MONOLIX, and R is required.Publication(s) applying modeling and simulation approaches to oncology, hematology, and immunology is preferred.Proficiency with systems modeling approaches such as differential equation, logic, stochastic, agent-based, or other advanced mechanistic modeling approaches is essential.Demonstrated ability for critical thinking and strong analytical skills to evaluate complex information to identify key scientific questions related to projects.Ability to prioritize and manage multiple projects while meeting project deadlines.In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply. -TRAVEL REQUIREMENTS: 10%WHAT TAKEDA CAN OFFER YOU: 401(k) with company match and Annual Retirement Contribution PlanTuition reimbursement Company match of charitable contributionsHealth & Wellness programs including onsite flu shots and health screeningsGenerous time off for vacation and the option to purchase additional vacation daysCommunity Outreach ProgramsEmpowering Our People to ShineDiscover more at takedajobs.comNo Phone Calls or Recruiters Please.*LI-KBEEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.LocationsBoston, MAWorker TypeEmployeeWorker Sub-TypeRegularTime TypeFull time

Keywords: Takeda Pharmaceutical, Billerica , Oncology Quantitative Systems Pharmacology Modeler - Quantitative Solutions, Healthcare , Billerica, Massachusetts

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